• Visibly brightens and evens skin tone

• Reduces dark spots, melasma, and sun damage

• Improves texture and refines pores

• Helps clear adult acne 

• Supports a strong skin barrier

Tretinoin Active Renewal Cream is appropriate for:

• Anyone with fine lines, melasma, sun damage, blotchy tone, or hyperpigmentation

• Adults with acne who need a gentle retinoid

• Women in midlife dealing with drier, thinner skin 

To find out if Tretinoin Active Renewal Cream is right for you, submit a prescription request or book a visit with a Midi clinician. Once you’ve reviewed your medical history and current symptoms together, your clinician will advise on whether this might be a helpful addition to your skincare routine. She may also recommend additional solutions that support skin health.

Follow these tips when using the product: 

• Apply to cleansed, dry skin. 

• Dispense a pea-size pump onto fingertips. Dot on forehead, cheeks, and chin, then spread thinly over the face, avoiding eyelids, nostrils, and lips. 

• If skin is sensitive to the product, apply a moisturizer before applying Tretinoin Active Renewal Cream.

• Use SPF 30+ during the day.

Start slowly:

• Weeks 1–2: Use every 3rd night

• Weeks 3–4: Use every other night

• Week 5+: Use nightly, as tolerated

Active ingredients: Tretinoin 0.05%; Tranexamic Acid 3%; Niacinamide 4%; Panthenol 3%

• Sun sensitivity (always wear SPF 30+ when using this product).

• Mild irritation can occur, including redness, dryness, peeling and/or flaking.

• It’s safe to use the following products: Estriol Cream, hyaluronic-acid serums, peptides, ceramide moisturizers, azelaic acid, mineral sunscreen.

• Skin irritation may occur when using the following products: Leave-on glycolic or salicylic acids, alcohol toners, abrasive scrubs, benzoyl peroxide, or other leave-on retinoids.

• Ask your clinician for guidance if you have any concerns.

• This product is not recommended during pregnancy.

• Use with caution if breastfeeding and avoid chest area.

• Always wear sunscreen when using tretinoin.

• Avoid combining with other exfoliants or retinoids unless directed by your clinician.

View Tretinoin Active Renewal Cream safety information