Copper Peptide Repair Cream 

Compared to the support Midi’s Estriol+ Face cream may help provide for elasticity and hydration caused by drops in estrogen, Midi's Copper Peptide Repair Cream works differently. Powered by 0.1% GHK-Cu, this formula helps support the skin's natural repair process — helping skin rebuild and recover. It's also paired with niacinamide to help calm visible reactivity and strengthen the skin barrier, and hyaluronic acid to help improve hydration retention.

Midi’s copper peptide repair cream is formulated to help skin look firmer and feel stronger, without triggering redness, peeling, or flare-ups. This makes it especially well suited for sensitive or reactive skin and a supportive partner to treatments like tretinoin.

Yes, depending on which products you use we recommend the following:

• Estriol+ Face Cream and/or Estriol+ Eye Cream: These products work great together, simply apply Midi’s Copper Peptide Repair cream prior to any estriol cream.
• Tretinoin: We recommend alternating nights with tretinoin when used together. Please consult your clinician for medical advice.
• Hydroquinone: We recommend alternating the Copper Peptide Repair cream  with hydroquinone when used together. Consider using the Copper Peptide Repair cream in the morning and hydroquinone at night. Please consult your clinician for medical advice.

Apply a pea-sized amount to the face and neck, either in the morning or at night. Apply before any estriol creams, serums, or moisturizers. Always follow any skincare routine with an SPF.

Most people tolerate GHK-Cu well. Possible mild side effects include slight redness, mild skin irritation, and dryness when used with other strong skincare products. These effects are usually temporary. If you have any concerns, please contact your clinician.

Most women begin to see certain results starting within two weeks with continued improvement over time.

1. Weeks 1–2: Skin may feel more comfortable, hydrated, and balanced 
2. Weeks 4–8: Texture can look smoother and skin can appear calmer and healthier 
3. Weeks 8–12+: Skin may look firmer, more resilient, and less crepey with continued use

 The cream may appear light blue due to the copper content in the formula. This color fades upon application and will not stain the skin or clothes/fabric.