Midi

Finally, hormone-first weight care built for women. Learn more.

Jan 21, 2026

Best Creatine Supplement for Women

Medically reviewed by:
woman on yoga mat stretching
The Big Picture

Creatine has officially made the jump from gym bro locker room talk to women’s wellness feeds—but if you’re in midlife, you may be wondering whether it’s actually right for you. The truth is, creatine isn’t just for bodybuilders or twenty-somethings chasing big gains. Research suggests creatine supplementation can support muscle mass, strength, and even cognitive function during perimenopause and menopause. The real question isn’t whether women should consider creatine, but how to choose the best creatine supplement for women, what form actually works, and how much you really need. Here’s what the science says—and how to make creatine work for your body in midlife.

Maybe you’ve overheard women talking about creatine supplements while you were stashing stuff in your gym locker or waiting in line to order a latte. The topic’s gotten very buzzy—and as research continues to come out about creatine supplements, we can see why there’s all this curiosity about its potential for building strength and boosting energy.

Creatine is a natural substance that’s made in your body, mainly in the liver. You can also get it from dining on meat or fish or by taking a supplement. Either way, creatine helps your muscles and your brain recharge energy quickly. So it offers wide-ranging benefits both inside and outside of the gym, including effects on strength, energy, and body composition. 

Because the creatine supplement industry has exploded, it can feel tricky to choose the right one. To help you pick the best creatine for women over age 40, we’re here with advice, as well as information on dosing, safety, and how to add creatine to your vitamin stack with minimal side effects.

IN THIS ARTICLE

Creatine Basics for Women

Here’s the 101 on how creatine works in your body. Let’s say you’re lifting a heavy box. To do that, your muscles need to access energy quickly. The main energy source for muscles (in fact, for all cells) is a molecule called ATP—and creatine helps quickly regenerate ATP. It does that during high-intensity exercise, and that in turn increases your exercise capacity. 

This means you may be able to work out a bit longer or harder—say, lift somewhat heavier weights, do more reps, and keep the activity going. Another way creatine helps is by drawing water into the muscle cells, which may stimulate muscle growth. There’s also research showing that creatine supplements could give your memory and processing speed a bit of a boost. 

For women over 40 years old, creatine may have additional perks, increasing functional strength and lean mass, along with boosting mood and energy. And that energy lift can help you exercise more consistently. 

Creatine works best alongside healthy habits—for example, it helps with muscle mass and strength when combined with regular resistance exercise. And it may help your brain feel sharp, but you also have to make time to de-stress and get a healthy amount of sleep.

To bust one myth: Creatine is not a fat burner. In fact, you might see a small increase in water weight when you first start taking it. (We’ll get more into that later.) 

What to Look For in a Creatine Supplement for Women

Shopping for a creatine supplement can be bewildering, given all the options on store shelves and online. So here are the seven factors to consider to help you in your search. Note: Midi Health’s Creatine+ supplement checks all these boxes. It also contains fennel seed extract, which can help you avoid digestive discomfort. 

  • Choose creatine monohydrate: This form is extensively studied for its effectiveness and is the gold standard for absorption.
  • Look for testing: You want to buy creatine from a trusted brand, so look for one that uses third-party testing through programs like NSF, USP, or Informed Choice. You can also check the brand’s website for a COA (certificate of analysis, a lab report that shows what’s in the supplement), potency testing, and GMP Compliance (Good Manufacturing Practices, a set of quality standards).
  • Look at the dosage: It should be clear on the packaging exactly how much creatine is in each serving. Midi recommends that women aim for 3-5 grams (g) per day, but you might go up to 4 to 5 g per day if you’re doing heavier training.
  • Read the ingredients: Look for a supplement with minimal additives. Some added sugar may be okay, depending on your diet. Avoid supplements that contain added stimulants in the formula.
  • Consider the form: Do you want the convenience of a gummy? A micronized powder that dissolves easily in liquids? Easy-to-take capsules? Each has benefits, so consider your lifestyle and preferences.
  • Look for allergens: If you have an allergen or dietary concern, read the product labeling for inactive or other ingredients.
  • Note this if you’re an athlete: If you’re required to undergo drug testing, make sure any supplement you choose—creatine or otherwise—is NSF Certified for Sport

Comparing Different Types

Creatine comes in many forms. Here’s a quick primer on different varieties:

  • Chews or gummies: These tend to taste good and be easier to stick with. Some can contain sugar, so look for ones with minimal amounts. (Midi’s Creatine+ has only 5 g of sugar per dose of 3 g.)
  • Powder: Micronized creatine monohydrate dissolves in liquids, so it has less of a thick, chalky taste.
  • Capsules: If you’re OK with swallowing capsules daily, this can be a convenient option.
  • Creatine HCl (hydrochloride): This hasn’t been proven to be better than monohydrate, and these products are often more expensive.

Best Creatine for Women Over 40

Whew, that’s a lot of info. We’ll break down our selection criteria listed above into easy-to-understand highlights:

  • Best form of creatine: Creatine monohydrate
  • Best dosage: 3 to 5 g of creatine per day
  • Ensure safety: Look for products that are third-party tested
  • Best form: Gummies are good for ease and convenience
  • Avoid extras: Don’t buy blends with additional stimulants

Image showing bottle of Midi's Creatine+

How Much Creatine to Take and When

The ideal standard daily dose of creatine for women is 3 g, though you can go up to 4 to 5 g per day. The timing of when to dose doesn’t matter as much as consistency, so plan to take creatine when you’ll remember it. One way to build a healthy habit is to try something called habit stacking—meaning, you tack on the habit you’re trying to establish (taking creatine) with a habit that’s already in place (for example, eating breakfast or washing your face).

If you experience bloating, you can ease that by splitting the dose in half, taking it with food, and drinking enough fluids (water, preferably) throughout the day.
You may have heard about creatine loading (especially if you’ve happened upon a bro podcast about science!). This is when you take a large dose of creatine (20 g per day) for the first 5 to 7 days to fully saturate your muscles by the end of the week. Then, you switch to a maintenance phase with a lower dosage (3 to 5 g per day). 

Research has shown that this technique is not necessary to get the benefits of creatine, and there’s a higher risk of side effects like bloating or GI discomfort. 

Creatine and Weight Loss

Because creatine is associated with fitness, many people naturally wonder, Can creatine help you lose weight? The short answer: It’s not a weight loss supplement, but it does have some indirect benefits that can help with weight loss but they require some effort. For example, if taking creatine helps you push harder in the gym, the increased stress you’re putting on your muscles stimulates their growth and strength. More lean body mass equals a faster metabolism, and that can contribute to a healthy weight. In other words, it may help, but don't just expect the pounds to just fall off.

Lean muscle helps in another way. As research explains, when estrogen declines during menopause, we start to lose muscle mass, which indirectly encourages fat gain as the years go on. Building a leaner body mass may help you avoid a condition like sarcopenia, a loss of muscle mass and strength that leads to weakness in older adults.

When you start taking creatine, you actually might put on a couple of pounds due to water retention, but only at the very beginning. Creatine pulls water into your muscles, but this weight is expected to go away as your body adjusts.Tracking other measurements, like your waist circumference and how clothes fit, can show progress in ways that the scale may not. 

image showcasing Midi's supplements with link to our quiz

How to Pair Creatine with Training and Nutrition

Combining creatine and strength training is crucial to getting the most out of your supplementation. Resistance exercise—lifting free or machine weights, doing body weight exercises—forces muscles to contract against an external load, improving muscle mass, strength, and function. Gradually increasing the load (upping the weight, reps, or sets) is what’s called progressive overload, which is what’s needed to stimulate muscles to make these positive changes.
All kinds of regular physical activity—including walking, taking regular dance breaks, doing extra flights of stairs—has a load of perks for midlife women, leading to better sleep and mood, as well as encouraging healthier eating habits. 

Those healthier eating habits should include getting enough protein. Remember, animal foods like poultry, lean red meat, and fish also contain creatine, which your muscles can use. If you don’t eat meat or not much of it, focus on hitting protein targets with dairy plus plant-based sources like soy, fortified plant-based dairy, nuts, seeds, beans, and lentils. 

A good training and nutrition plan requires adequate recovery. Sleep can be tough to come by during menopause, but aim for at least 7 hours per night.

Safety and Side Effects

Creatine is a safe supplement for many people, but that doesn’t mean it's right for everyone. Side effects to look out for include temporary weight gain from water retention, as well as mild GI discomfort. These should diminish as your body gets used to creatine.

If you have preexisting kidney problems or are pregnant or breastfeeding, talk with your clinician before starting creatine. It’s possible that blood levels of creatine may increase in some people taking a supplement, so tell your doctors what you’re taking, especially if you’re getting lab work done. 

Troubleshooting

If you’re getting tripped up by how you feel on creatine or aren’t seeing the results you expected, there are a couple ways to fix this:

Dealing with GI side effects (like bloat, discomfort, constipation)?

What you can do:

  • Try micronized powder or capsules.
  • If you’re doing a loading phase, instead switch to a maintenance dose (about 3 g per day).
  • Split the dose in two and take with food.
  • Gradually increase fiber intake.
  • Try drinking more water.
  • Talk with your doctor about temporarily taking stool softeners or a magnesium oxide or citrate supplement, if you’re experiencing constipation.

Not seeing a difference in the gym?

What you can do:

  • Take creatine consistently. Change the time of day you take it, if forgetting is an issue.
  • Look at your workout—are you following a progressive overload program? If not, consider a session with a certified personal trainer to help plan this out.
  • Make sure lifestyle habits like sleep, stress management, and healthy eating are all prioritized; these factors are key for results. 

Top Creatine Picks for Women by Need

Midi’s Creatine+ is our recommendation for a gummy supplement. Each dose is 3 g of creatine monohydrate, and the added fennel seed extract makes it especially gut-friendly.

If you’re looking for creatine in a different form, here are some recommendations: 

Best value monohydrate powder

BulkSupplements.com Creatine Monohydrate: This micronized creatine monohydrate is unflavored, with no added sugar, and each 2-teaspoon serving supplies 5 g of creatine. 

Best capsule format

Nature’s Nutrition Creatine Monohydrate: Aside from third-party testing and micronized creatine powder, there are 4 capsules per 3-g serving of creatine, which is fewer than some other brands. 

Best “Certified for Sport” option

Garden of Life Creatine Plus Probiotics Powder: Each 2-teaspoon serving of this unflavored powder contains 5 g of micronized creatine monohydrate, plus probiotics for digestive health. 

Best vegan/allergenic-clean label

Bloom Nutrition Creatine Monohydrate: Micronized creatine monohydrate in a raspberry-lemon flavor, sweetened with stevia. (There’s also an unflavored version.) This one is gluten-free and vegan-friendly.

Best travel packs 

Thorne Creatine: Each single-serve stick pack provides 5 g of creatine monohydrate to mix with 8 ounces of liquid. It’s also NSF Certified for Sport.

Key Takeaways

  • Creatine supports strength, energy, and lean muscle in women over 40, helping counter age- and estrogen-related muscle loss.
  • The best creatine supplement for women is creatine monohydrate, taken consistently at 3–5 g per day.
  • Creatine isn’t a fat-loss supplement, but improved workout performance and muscle preservation can support healthier body composition over time.
  • Initial weight gain is usually temporary water retention, not fat, and typically levels out as your body adjusts.
  • Choose a high-quality creatine with minimal additives and a form (gummy, powder, capsule) you’ll take daily.

Frequently Asked Questions (FAQs)

Which creatine is best for women?

When it comes to creatine supplements for women, look for a micronized creatine monohydrate, a type of creatine that’s well studied. 

Is creatine worth it for females?

Creatine can have many benefits for females during every stage, including premenopause, perimenopause, and postmenopause. Creatine may help preserve muscle mass and strength as well as bone health, improve energy, and support cognitive function and mood.

What brand of creatine is the most effective?

When looking for an effective creatine, it’s more important to find one that is a micronized creatine monohydrate, has third-party testing, and can be taken in a 3- to 5-g serving size.

Why did I gain 10 pounds after taking creatine?

Although creatine does cause initial mild weight gain due to water retention, that effect is temporary. If you have gained 10 pounds since taking creatine, it may be due to lifestyle changes (such as consuming more calories) or linked to an underlying medical condition. If you can’t figure out why you gained the weight, see your doctor for an evaluation.

Can women take creatine every day?

Yes, women can take creatine every day. In fact, consistently taking a dose of 3 to 5 g daily is needed to get the benefits, helping you maintain muscle saturation. It doesn’t need to be taken the same time every day, though doing that can help you remember to take it.

How Midi Can Help You

If you’re in perimenopause or menopause and want guidance from clinicians who specialize in women’s midlife health, book a virtual visit with Midi today.

Hormonal change is at the root of dozens of symptoms women experience in the years before and after their period stops.

Our trained menopause specialists can help you connect the dots to guide you towards safe, effective solutions.

Whether you need personalized guidance or a prescription routine to tackle symptoms—including brain fog, hot flashes, sleep trouble, mood swings, and weight gain—we’ve got you covered. Learn more here.

EDITORIAL STANDARDS

Midi’s mission is to revolutionize healthcare for women at midlife, wherever they live and whatever their health story. We believe that starts with education, to help all of us understand our always-changing bodies and health needs. Our core values guide everything we do, including standards that ensure the quality and trustworthiness of our content and editorial processes. We’re committed to providing information that is up-to-date, accurate, and relies on evidence-based research and peer-reviewed journals. For more details on our editorial process, see here.